Basic Information
VIS ID
TVIS44003384
Fusion event
HTLV-1-chrX integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
p11.23
Reference genome
GRCh37/hg19
Start
49636249/49871646 (Hg38)
End
49636249/49871646 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1587/Upstream/2284141; hsa-let-7f-2/Downstream/131502;
Nearest TSS
ENST00000429181/Upstream/40962; ENST00000621775/Downstream/7595;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/272099, chrX-CpG: 57/Downstream/7657
Nearby gene
USP27X-AS1(No orient, 5078)
Upstream sequence
agtgaatacacatgtaattgtggagacattgctgaatttccttctattgaggttatataatttcattTGTATTGCTTTTTGTGGTTTTAAAAGGATTAAT
Downstream sequence
ATTTTGAAAAAGAATTAAAAGTGTGATTAAGATTTTTATCTGCCAATTTGGGTGCAATATACCCTTCCCCActcttcaagcttgaaagaggcattcagga
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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