VISDB Viral Integration Site DataBase

VIS ID

TVIS44003393

Fusion event

HTLV-1-SH3PXD2A integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr10

Cytoband

q24.33

Reference genome

Start

End

105490578/103730820 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

FRA10D ; FRA10A ; FRA10B

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-130b-3p ; hsa-mir-124-3p ; hsa-mir-93-5p ; hsa-mir-33a-5p ; hsa-mir-24-3p ; hsa-mir-331-3p ; hsa-let-7b-5p ; hsa-mir-155-5p ; hsa-mir-212-5p ; hsa-mir-377-3p ; hsa-mir-8485 ; hsa-mir-148a-3p ; hsa-mir-152-3p ; hsa-mir-148b-3p ; hsa-mir-6818-5p ; hsa-mir-6867-5p ; hsa-mir-1257 ; hsa-mir-642b-3p ; hsa-mir-642a-3p ; hsa-mir-6849-3p ; hsa-mir-425-5p ; hsa-mir-603 ; hsa-mir-2110 ; hsa-mir-491-5p ; hsa-mir-6769b-5p ; hsa-mir-6769a-5p ; hsa-mir-654-5p ; hsa-mir-541-3p ; hsa-mir-486-3p ; hsa-mir-6780b-5p ; hsa-mir-4725-3p ; hsa-mir-4271 ; hsa-mir-4747-5p ; hsa-mir-5196-5p ; hsa-mir-3202 ; hsa-mir-657 ; hsa-mir-3665 ; hsa-mir-6873-3p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-4639-3p ; hsa-mir-6875-3p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-4753-3p ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-4469 ; hsa-mir-6832-3p ; hsa-mir-4667-3p ; hsa-mir-1470 ; hsa-mir-5571-5p ; hsa-mir-342-3p ; hsa-mir-5003-5p ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-30a-3p ; hsa-mir-3157-5p ; hsa-mir-5695 ; hsa-mir-6769a-3p ; hsa-mir-3145-5p ; hsa-mir-130b-5p ; hsa-mir-5692a ; hsa-mir-4643 ; hsa-mir-4717-3p ; hsa-mir-942-3p ; hsa-mir-448 ; hsa-mir-153-3p ; hsa-mir-4672 ; hsa-mir-5689 ; hsa-mir-6768-5p ; hsa-mir-548o-3p ; hsa-mir-1323 ; hsa-mir-5096 ; hsa-mir-3614-3p ; hsa-mir-6803-5p ; hsa-mir-6751-5p ; hsa-mir-7109-5p ; hsa-mir-4665-5p ; hsa-mir-1275 ; hsa-mir-561-5p ; hsa-mir-615-5p ; hsa-mir-6885-5p ; hsa-mir-328-5p ; hsa-mir-6887-5p ; hsa-mir-6795-5p ; hsa-mir-3189-3p ; hsa-mir-6830-5p ; hsa-mir-6732-5p ; hsa-mir-4428 ; hsa-mir-32-5p ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-30e-5p ; hsa-mir-30d-5p ; hsa-mir-30c-5p ; hsa-mir-30a-5p ; hsa-mir-30b-5p ; hsa-mir-200c-3p

Nearest miRNA

hsa-mir-107/Upstream/336419; hsa-mir-202/Downstream/317269;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/37348, chr10-CpG: 73/Downstream/123933

Upstream sequence

cttagggctgggcttcctgtttattagtgaagacacagagacgacaaatgtggccctcaaggagctcatagtctgggagaagacagacacacagaagtta

Downstream sequence

ccctcctgcagaggagaaatgcacagagtcggggtgggcgcagtcctctgggggcagaatggcaggagtgatcagcttttcctggggagtcatgaggctt