Basic Information
VIS ID
TVIS44003396
Fusion event
HTLV-1-TAF1D integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q21
Reference genome
End
93472972/93739806 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-590-3p ; hsa-mir-98-5p ; hsa-mir-1296-5p ; hsa-mir-452-3p ; hsa-mir-4291 ; hsa-mir-761 ; hsa-mir-3619-5p ; hsa-mir-214-3p ; hsa-mir-922 ; hsa-mir-4760-3p ; hsa-mir-10a-3p ; hsa-mir-382-3p ; hsa-mir-1304-5p ; hsa-mir-7150 ; hsa-mir-6807-5p ; hsa-mir-891a-3p ; hsa-mir-3688-5p ; hsa-mir-4736 ; hsa-mir-4763-3p ; hsa-mir-1207-5p ; hsa-mir-548v ; hsa-mir-3975 ; hsa-mir-1233-3p ; hsa-mir-1225-3p ; hsa-mir-1273f ; hsa-mir-4708-5p ; hsa-mir-6088 ; hsa-mir-4770 ; hsa-mir-143-3p ; hsa-mir-139-5p ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-6500-3p ; hsa-mir-3614-5p ; hsa-mir-4799-5p ; hsa-mir-591 ; hsa-mir-4738-3p ; hsa-mir-20a-3p ; hsa-mir-4780 ; hsa-mir-885-5p ; hsa-mir-6512-5p ; hsa-mir-548av-3p ; hsa-mir-548e-5p ; hsa-mir-6807-3p ; hsa-mir-217 ; hsa-mir-4755-5p ; hsa-mir-335-3p ; hsa-mir-6726-3p ; hsa-mir-3157-5p ; hsa-mir-4764-5p ; hsa-mir-6756-3p ; hsa-mir-3127-3p ; hsa-mir-1250-3p ; hsa-mir-5685 ; hsa-mir-4690-3p ; hsa-mir-6501-3p ; hsa-mir-4495 ; hsa-mir-15a-3p ; hsa-mir-6769a-3p ; hsa-mir-2278 ; hsa-mir-4753-5p ; hsa-mir-522-3p ; hsa-mir-224-3p ; hsa-mir-4694-3p ; hsa-mir-6768-3p ; hsa-mir-1298-5p ; hsa-mir-302c-5p ; hsa-mir-222-5p ; hsa-mir-3129-5p ; hsa-mir-199b-3p ; hsa-mir-199a-3p ; hsa-mir-936 ; hsa-mir-4719 ; hsa-mir-5094 ; hsa-mir-5680 ; hsa-mir-6753-5p ; hsa-mir-1911-3p ; hsa-mir-4731-3p ; hsa-mir-429 ; hsa-mir-200c-3p ; hsa-mir-200b-3p ; hsa-mir-203b-3p ; hsa-mir-4539 ; hsa-mir-576-3p ; hsa-mir-6739-5p ; hsa-mir-6733-5p ; hsa-mir-3153 ; hsa-mir-4668-5p ; hsa-mir-4646-5p ; hsa-mir-204-3p ; hsa-mir-3973 ; hsa-mir-562
Nearest miRNA
hsa-mir-10392/Upstream/6042; hsa-let-7a-2/Downstream/726689;
Upstream sequence
TCCTAAAGCAAAGTGTGCCCTATATAAACCAGGAAAAGGATCTCCAATCAATAAACCATTTTAAACTCCTAATCACCTCTCCATTATAATTCCTAGATTC
Downstream sequence
TTCATTCCTAGATTCATTTAAGCAACTGAACTTTGTCATATTGTAtctttgccattattggtggaaactgacaagttctgaattctcaacctttttcaat
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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