Basic Information
VIS ID
TVIS44003411
Fusion event
HTLV-1-SNRPN integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
25185583/24940436 (Hg38)
End
25185583/24940436 (Hg38)
Orient
+
Location type
Intronic
Target gene
SNRPN
miRNAs that regulate target gene
hsa-mir-26b-5p
Nearest miRNA
hsa-mir-1268a/Upstream/1378305; hsa-mir-10393/Downstream/908311;
Nearest TSS
ENST00000557528/Upstream/83835; ENST00000577949/Downstream/14491;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/61875, chr15-CpG: 77/Downstream/14452
Upstream sequence
ggtcttatatttaggtctctgatccatttcaagttcatttttgtatatgatgtaaggaaagggtccaacttcattcttttgcatgtggatatccagtttt
Downstream sequence
cccagtaccacgtgttgaaaaggctgtcctttccccattgaaggtcttggcacaattgttgaaaatcatttgaccatatggaagagtttatttctgggat
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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