Basic Information
VIS ID
TVIS44003414
Fusion event
HTLV-1-chr18 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
25254708/27674744 (Hg38)
End
25254708/27674744 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1-2/Upstream/1083209; hsa-mir-122/Downstream/2624166;
Nearest TSS
ENST00000575820/Upstream/79580; ENST00000423367/Downstream/279775;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/489201, chr18-CpG: 257/Downstream/500706
Nearby gene
CDH2(-276219) ;
Upstream sequence
ATTCCAAGTCTTTCCTTGTGCCTTGAAGCTCTTCCCCTAGCCCTGTCCCGTTGATCCCTCTGACTCCTCCATTCCTTCATACCCCAGAACTACATGGTCA
Downstream sequence
TATGGCACTCATTTCCCAGTCCTATCTTATGATCTTGTTCTTTATACAAAATCCAAACAACCTTCCTACAGCCTGAATACAGTTATCATGACCAACTTTT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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