Basic Information
VIS ID
TVIS44003419
Fusion event
HTLV-1-EFHD1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q37.1
Reference genome
GRCh37/hg19
Start
233505181/232640471 (Hg38)
End
233505181/232640471 (Hg38)
Orient
+
Location type
Intronic
Target gene
EFHD1
miRNAs that regulate target gene
hsa-mir-193b-3p
Nearest miRNA
hsa-mir-10b/Upstream/89898; hsa-mir-149/Downstream/4870460;
Nearest TSS
ENST00000437798/Upstream/2330; ENST00000427698/Downstream/21224;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/5794, chr2-CpG: 66/Downstream/56642
Upstream sequence
GGTCTCCTCCAGTGTTCCCAGCTCTGGGCTTCTGTGGCCAGCACTGTCCATATGTCTGCTAGTGTGTGCTCCTGTGGTACCATATCATGATGATGATGAC
Downstream sequence
GATGATCACCATGAGCCCCTTTCCAACCTGCTATGAGCTattcattcactcattcattttttcattcattTAGCTAAGCACCTGCCAGGTGCCAGTTTAT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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