Basic Information
VIS ID
TVIS44003423
Fusion event
HTLV-1-chr20 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
p12.2
Reference genome
GRCh37/hg19
Start
11870382/11889734 (Hg38)
End
11870382/11889734 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA20B
Nearest miRNA
hsa-mir-103a-2/Upstream/1240039; hsa-mir-1-1/Downstream/6580881;
Nearest TSS
ENST00000382410/Upstream/19019; ENST00000450368/Downstream/989;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/202385, chr20-CpG: 126/Downstream/992
Nearby gene
BTBD3(+989) ;
Upstream sequence
ttttgttgtccaaagcccaggtgtctttcactatgtatgctgtctctcAAATTAATGGTTTTTCATCTGAGCAGAAATACGTTCTCCCAGGGCCAAACTC
Downstream sequence
TTGCTAAAAGAAGCATCCACTTGTCCTAACAGTATTGTATAGGTCTAATTTATCCACCGATATACATTTTGCCAAGGATGATGATCTGATCTAATGAAGT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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