Basic Information
VIS ID
TVIS44003449
Fusion event
HTLV-1-CATSPERB integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q32.12
Reference genome
GRCh37/hg19
Start
92060858/91594514 (Hg38)
End
92060858/91594514 (Hg38)
Orient
-
Location type
Intronic
Target gene
CATSPERB
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-26b-5p ; hsa-mir-23b-3p
Nearest miRNA
hsa-mir-1260a/Upstream/14328224; hsa-mir-1185-1/Downstream/2353712;
Nearest TSS
ENST00000550708/Upstream/1962; ENST00000553427/Downstream/51721;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/19982, chr14-CpG: 57/Downstream/241343
Upstream sequence
catgtatacatatgtgacaaacctgcacgttgtgcacatgtaccctaaaacttaaagtataataataataaaagaaaaaaaaaaaaagaagtgccttttg
Downstream sequence
aactctgccatgattctgaggcctccccagccatgtggaactgtaagtccaattaaacctctttcttttgtaaattgtaaattcttttgtaaattgccca
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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