Basic Information
VIS ID
TVIS44003454
Fusion event
HTLV-1-chr10 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q24.32
Reference genome
GRCh37/hg19
Start
103071846/101312089 (Hg38)
End
103071846/101312089 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Nearest miRNA
hsa-mir-107/Upstream/337005; hsa-mir-1307/Downstream/289328;
Nearest TSS
ENST00000439456/Upstream/1071; ENST00000475200/Downstream/11305;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/1342, chr10-CpG: 69/Downstream/41677
Nearby gene
BTRC(+41944) ;
Upstream sequence
taaatgttcaataaatgctagcaattattACTATCAGCAATTATTGAATAATCATCTGCTATGTCTTTGACacagggcaccatggaggttaggagcctgg
Downstream sequence
ggtttggagacagatgatctgagtttgaatcctggcttaacgcttattaactttgtggtcttggaaaagtcacagcttctctgagactcagtttccccat
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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