Basic Information
VIS ID
TVIS44003456
Fusion event
HTLV-1-chr20 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
p11.23
Reference genome
GRCh37/hg19
Start
19723632/19742988 (Hg38)
End
19723632/19742988 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA20A
Nearest miRNA
hsa-mir-103a-2/Upstream/1272297; hsa-mir-1-1/Downstream/6465198;
Nearest TSS
ENST00000382410/Upstream/458392; ENST00000432334/Downstream/14720;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/529730, chr20-CpG: 127/Downstream/14407
Nearby gene
SLC24A3(+20091) ;
Upstream sequence
GAGATAGTAGAAGAGACATGGAAAGCCATGGAGGCAAACAATGACATTTTTGGGAACGTTAAGTTTTTCACCTAGAGTATTAGAGAGCTAGAGAACCAGG
Downstream sequence
GAGTGTATTAGGAGATTAATTCTTGCTAACTGGGTAGAGGCGTCCAGGTAGGGCACTGAGAGAAGAGTTTGAAAGGAACCTTCTAATTTCTGCTCCTGGT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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