Basic Information
VIS ID
TVIS44003459
Fusion event
HTLV-1-SMIM15-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
60521892/61226065 (Hg38)
End
60521892/61226065 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA5H
Target gene
SMIM15-AS1
Nearest miRNA
hsa-mir-10397/Upstream/1522362; hsa-mir-103a-1/Downstream/10943402;
Nearest TSS
ENST00000502646/Upstream/63591; ENST00000252744/Downstream/26824;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/63238, chr5-CpG: 341/Downstream/104613
Upstream sequence
ggtctctacccggcaggttggctggtatgtactttatctgcaggcctctgtgccttctggattctggctggttgtgactaatggtgagtggtggcaagat
Downstream sequence
atcaaggggaaagagaaGAGTGATATTGAGCCTTTTTTCCCTCAGCTCCAACTGTGTGAAGACATTTAACCAAAGATAATGTCTCTCATGGGCCTCCTTG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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