Basic Information
VIS ID
TVIS44003472
Fusion event
HTLV-1-CCDC57 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
80071852/82113976 (Hg38)
End
80071852/82113976 (Hg38)
Orient
+
Location type
Intronic
Target gene
CCDC57
miRNAs that regulate target gene
hsa-mir-92a-3p
Nearest miRNA
hsa-mir-10226/Upstream/420107; hsa-mir-4525/Downstream/122692;
Nearest TSS
ENST00000595228/Upstream/7389; ENST00000579979/Downstream/13842;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/12968, chr17-CpG: 22/Downstream/13188
Upstream sequence
ttgaggccacagtgaaccaagattgtgccactgcactctggcctgggcaacagagcgagaATAAAGTAAATAAATAAGAGCCCCAAGGCCCCCTTGCCTG
Downstream sequence
CCCTGCAGCTTGGTCTTGCAGCTATGTTGGGCTGTCCATCTCACCTTGGCCATCAGGAGCCTGACGTGCACCTTCTAGTGCAGGTTACCTGGGCCCTGAG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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