Basic Information
VIS ID
TVIS44003474
Fusion event
HTLV-1-chr7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
46425696/46386098 (Hg38)
End
46425696/46386098 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1183/Upstream/1504298; hsa-mir-10399/Downstream/10569687;
Nearest TSS
ENST00000635602/Upstream/83978; ENST00000429010/Downstream/91842;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/464350, chr7-CpG: 86/Downstream/666548
Nearby gene
IGFBP3(-464825) ;
Nearest cancer related gene
IGFBP3(TSG, -464825) ;
Upstream sequence
GTGGCTGTAGTAAGACAGTGTTGCCATGGAATAAAACATCAAGATGGTTATTGAAAAAACTTTCCCAAATATGATTAAAAATAAGAAGATTCTTAGGTCC
Downstream sequence
ACAATGAATCACAAATGCTACTTCTCCCAGAGAAACCCAACACAGCAAGATTAACAGGCTCTGAGTCACATATTAAATACAACAAGGGCCCACTAAGTTA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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