Basic Information
VIS ID
TVIS44003479
Fusion event
HTLV-1-RUFY1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q35.3
Reference genome
GRCh37/hg19
Start
178989998/179562997 (Hg38)
End
178989998/179562997 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA5G
Target gene
RUFY1
Nearest miRNA
hsa-mir-10397/Upstream/2933497; hsa-mir-1229/Downstream/235281;
Nearest TSS
ENST00000502646/Upstream/366; ENST00000514238/Downstream/4513;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/2999, chr5-CpG: 31/Downstream/14499
Upstream sequence
CAACCAAAGGGCACTCACAGGAGGAAAAGGAACTACTGGTACACTCCTGGAATCACTGCTTCAGACACAGGTGGGCAGTTTTCTGAATAATACATTTTGG
Downstream sequence
GCCAGATTGTAGATTCCAGGCCCAAGGACATTTGTAATTTGTTAGGGTGGGACTAACGAATTATTTGCCATGTCTGGATTTGTCCTTGGGATCGCTATGC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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