VISDB Viral Integration Site DataBase

VIS ID

TVIS44003485

Fusion event

HTLV-1-NF2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr22

Cytoband

q12.2

Reference genome

Start

End

30029416/29633427 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-let-7a-5p ; hsa-mir-193b-3p ; hsa-mir-1229-3p ; hsa-mir-10a-5p ; hsa-mir-25-3p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-92b-3p ; hsa-mir-185-3p ; hsa-mir-423-5p ; hsa-mir-762 ; hsa-mir-3184-5p ; hsa-mir-4486 ; hsa-mir-4492 ; hsa-mir-4498 ; hsa-mir-4505 ; hsa-mir-5001-5p ; hsa-mir-5787 ; hsa-mir-6085 ; hsa-mir-6813-5p ; hsa-mir-1273e ; hsa-mir-4497 ; hsa-mir-25-5p ; hsa-mir-658 ; hsa-mir-4722-5p ; hsa-mir-1827 ; hsa-mir-6087 ; hsa-mir-219b-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-302f ; hsa-mir-4668-5p ; hsa-mir-31-5p ; hsa-mir-5681a ; hsa-mir-6779-5p ; hsa-mir-5589-3p ; hsa-mir-3922-5p ; hsa-mir-4312 ; hsa-mir-4696 ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-1273g-3p ; hsa-mir-7703 ; hsa-mir-6729-5p ; hsa-mir-4649-5p ; hsa-mir-1273a ; hsa-mir-661 ; hsa-mir-3117-5p ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-939-3p ; hsa-mir-6849-3p ; hsa-mir-508-5p ; hsa-mir-1228-5p ; hsa-mir-1253 ; hsa-mir-125a-5p ; hsa-mir-125b-5p ; hsa-mir-1285-3p ; hsa-mir-3187-5p ; hsa-mir-326 ; hsa-mir-330-5p ; hsa-mir-345-3p ; hsa-mir-378g ; hsa-mir-4319 ; hsa-mir-4488 ; hsa-mir-4732-3p ; hsa-mir-5189-5p ; hsa-mir-612 ; hsa-mir-670-5p ; hsa-mir-6770-5p ; hsa-mir-6860 ; hsa-mir-7113-3p ; hsa-mir-1207-5p ; hsa-mir-1471 ; hsa-mir-3148 ; hsa-mir-3917 ; hsa-mir-4281 ; hsa-mir-4434 ; hsa-mir-4449 ; hsa-mir-4516 ; hsa-mir-4690-5p ; hsa-mir-4736 ; hsa-mir-4746-5p ; hsa-mir-4763-3p ; hsa-mir-4783-3p ; hsa-mir-4795-5p ; hsa-mir-542-3p ; hsa-mir-5703 ; hsa-mir-6165 ; hsa-mir-6510-5p ; hsa-mir-7150

Nearest miRNA

hsa-mir-1286/Upstream/1173479; hsa-let-7a-3/Downstream/373622;

Nearest TSS

Nearest CpG islands

None/Target, chr22-CpG: 279/Upstream/29263, chr22-CpG: 131/Downstream/86714

Nearest cancer related gene

NF2(TSG, No orient, 0)

Upstream sequence

tctctcctttagtggaaccacctggtactcaagccagacacacaggtgtccctcttaattctgtctcctCTGGTCCTGTTCAGGCACCTGTTCTGTGACT

Downstream sequence

CTGCCTCTTTTCCGTTTCTCAGGCTGCCTTCTCTCCCTTCTACTGCCTTCCTTATGTCAGGGGTTGGCCTACTTTCTGGCCTTCTTGATCCAGGGCTTCT