Basic Information
VIS ID
TVIS44003489
Fusion event
HTLV-1-ITPKA integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q15.1
Reference genome
GRCh37/hg19
Start
41791500/41499302 (Hg38)
End
41791500/41499302 (Hg38)
Orient
+
Location type
Intronic
Target gene
ITPKA
miRNAs that regulate target gene
hsa-mir-193b-3p
Nearest miRNA
hsa-mir-1233-1/Upstream/4526401; hsa-mir-10393/Downstream/192283;
Nearest TSS
ENST00000557528/Upstream/5427; ENST00000491007/Downstream/2137;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/2961, chr15-CpG: 149/Downstream/2062
Upstream sequence
ttaaagattttaaaaggagttttgaaagtgatgtcatgcttctagtgggctgcttctggctacacccccagatccctggggattgggcacgtgatcacac
Downstream sequence
cctagtgtgccatgtaagggcttcagtaggaaagtgggagcaatgctgCCTGATGGAAGATGAGAAAGTGCCTGACATGCAATAGGCAGGTAGCATTTGA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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