Basic Information
VIS ID
TVIS44003492
Fusion event
HTLV-1-chr3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p11.1
Reference genome
GRCh37/hg19
Start
88827396/88778246 (Hg38)
End
88827396/88778246 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-let-7g/Upstream/1551969; hsa-mir-12124/Downstream/7581718;
Nearest TSS
ENST00000440867/Upstream/439723; ENST00000452448/Downstream/329278;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/627883, chr3-CpG: 41/Downstream/336239
Nearby gene
EPHA3(+329278) ;
Nearest cancer related gene
EPHA3(TSG, +329278) ;
Upstream sequence
tcaaaggaccagtagtgactactatgagcaactatatgccagtaaataggaaaaccaagaagaaatggatgaattcgtagacacaaacaacttaccaaca
Downstream sequence
ttgagtcatgaagaaatctgagagctgaatagatcaataataagcaacgagattagcaaagcctaagacccaaagccttcactgctgaattttagcaaac
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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