Basic Information
VIS ID
TVIS44003500
Fusion event
HTLV-1-TAFA2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
62502272/62108491 (Hg38)
End
62502272/62108491 (Hg38)
Orient
-
Location type
Intronic
Target gene
TAFA2
miRNAs that regulate target gene
hsa-mir-124-3p
Nearest miRNA
hsa-mir-1228/Upstream/4283799; hsa-let-7i/Downstream/151868;
Nearest TSS
ENST00000382841/Upstream/3563; ENST00000546718/Downstream/27545;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/2511765, chr12-CpG: 117/Downstream/82496
Upstream sequence
atgagcatttgggttggtcccaagtctttgctattgtgaacaatggtgcattaaatgtacatgtgtatatgtctttacagtagaatttataatcctttgg
Downstream sequence
gtacatacccagtaaggggattgctgggtcaaatggtatttctggttctagatccttgaggaatcgccacactgtcttccacaatggttgaactaattta
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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