VISDB Viral Integration Site DataBase

VIS ID

TVIS44003503

Fusion event

HTLV-1-IKZF3 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr17

Cytoband

q21.1

Reference genome

Start

End

38005451/39849198 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-125b-5p ; hsa-mir-661 ; hsa-mir-196a-3p ; hsa-mir-1233-3p ; hsa-mir-1225-3p ; hsa-mir-6860 ; hsa-mir-612 ; hsa-mir-5189-5p ; hsa-mir-3187-5p ; hsa-mir-1285-3p ; hsa-mir-939-3p ; hsa-mir-6840-3p ; hsa-mir-6849-3p ; hsa-mir-4433a-3p ; hsa-mir-5000-3p ; hsa-mir-4436a ; hsa-mir-5000-5p ; hsa-mir-665 ; hsa-mir-8055 ; hsa-mir-6807-5p ; hsa-mir-4266 ; hsa-mir-6894-5p ; hsa-mir-7160-5p ; hsa-mir-3135a ; hsa-mir-4445-5p ; hsa-mir-202-3p ; hsa-mir-98-5p ; hsa-mir-4500 ; hsa-mir-4458 ; hsa-let-7i-5p ; hsa-let-7g-5p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-let-7d-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-6823-3p ; hsa-mir-2114-3p ; hsa-mir-7162-3p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-4779 ; hsa-mir-4695-5p ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-766-3p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-5699-3p ; hsa-mir-4421 ; hsa-mir-6748-3p ; hsa-mir-759 ; hsa-mir-5586-3p ; hsa-mir-508-5p ; hsa-mir-4797-5p ; hsa-mir-651-5p ; hsa-mir-7977 ; hsa-mir-342-3p ; hsa-mir-383-3p ; hsa-mir-1228-3p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-498 ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-23b-5p ; hsa-mir-23a-5p ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-562 ; hsa-mir-129-5p ; hsa-mir-3912-5p ; hsa-mir-4309 ; hsa-mir-3198 ; hsa-mir-6794-3p ; hsa-mir-6755-3p ; hsa-mir-198 ; hsa-mir-4294 ; hsa-mir-1289 ; hsa-mir-8082 ; hsa-mir-4534 ; hsa-mir-1273f ; hsa-mir-4708-5p ; hsa-mir-6088 ; hsa-mir-4770 ; hsa-mir-143-3p ; hsa-mir-367-5p ; hsa-mir-1267 ; hsa-mir-1304-3p ; hsa-mir-4639-3p ; hsa-mir-6514-5p ; hsa-mir-3664-5p ; hsa-mir-4279 ; hsa-mir-887-5p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-890 ; hsa-mir-1200 ; hsa-mir-4324 ; hsa-mir-544b ; hsa-mir-6869-5p ; hsa-mir-1273g-3p ; hsa-mir-1292-3p ; hsa-mir-4252 ; hsa-mir-4793-3p ; hsa-mir-7703

Nearest miRNA

hsa-mir-1180/Upstream/122637; hsa-mir-10226/Downstream/177134;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/94048, chr17-CpG: 37/Downstream/14930

Nearest cancer related gene

IKZF3(TSG, No orient, 0)

Upstream sequence

tacagactgggataaagtatttgtattacacatctgacaaagtacacatTACTggctgggtgcagtggctcaagcctgtaatcccagcactttgggaggc

Downstream sequence

caaggcagacaaaccacctgaggtcaggagtttgagaccagcctggccaacatgctaaaaccctgtctctactaaaacaatacaaaaattagccaggtgt