Basic Information
VIS ID
TVIS44003512
Fusion event
HTLV-1-TRIM71 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p22.3
Reference genome
End
32928403/32886911 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-let-7c-5p ; hsa-let-7a-5p ; hsa-mir-125b-5p ; hsa-mir-17-5p ; hsa-let-7b-5p ; hsa-let-7d-5p ; hsa-let-7e-5p ; hsa-let-7f-5p ; hsa-mir-98-5p ; hsa-let-7g-5p ; hsa-let-7i-5p ; hsa-mir-3607-3p ; hsa-mir-4458 ; hsa-mir-4500 ; hsa-mir-3927-3p ; hsa-mir-3935 ; hsa-mir-4495 ; hsa-mir-5093 ; hsa-mir-5680 ; hsa-mir-6831-5p ; hsa-mir-3117-3p ; hsa-mir-3169 ; hsa-mir-3908 ; hsa-mir-4503 ; hsa-mir-4759 ; hsa-mir-8083 ; hsa-mir-651-3p ; hsa-mir-1252-5p ; hsa-mir-593-5p ; hsa-mir-383-5p ; hsa-mir-6839-5p ; hsa-mir-378j ; hsa-mir-2115-3p ; hsa-mir-1243 ; hsa-mir-3156-5p ; hsa-mir-182-5p ; hsa-mir-1271-5p ; hsa-mir-96-5p ; hsa-mir-183-5p ; hsa-mir-5572 ; hsa-mir-6855-5p ; hsa-mir-3170 ; hsa-mir-6819-5p ; hsa-mir-6812-5p ; hsa-mir-6737-5p ; hsa-mir-4325 ; hsa-mir-6858-5p ; hsa-mir-4689 ; hsa-mir-1224-5p ; hsa-mir-3915 ; hsa-mir-4473 ; hsa-mir-4671-3p ; hsa-mir-6881-5p ; hsa-mir-1256 ; hsa-mir-4653-3p ; hsa-mir-4784 ; hsa-mir-3150b-3p ; hsa-mir-3614-5p ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-4761-3p ; hsa-mir-2110 ; hsa-mir-6780b-5p ; hsa-mir-4725-3p ; hsa-mir-4271 ; hsa-mir-4468 ; hsa-mir-7155-5p ; hsa-mir-637 ; hsa-mir-8089 ; hsa-mir-4700-5p ; hsa-mir-4667-5p ; hsa-mir-1298-3p ; hsa-mir-2278 ; hsa-mir-1276 ; hsa-mir-3686 ; hsa-mir-452-3p ; hsa-mir-6792-5p ; hsa-mir-202-3p ; hsa-mir-203a-3p ; hsa-mir-34c-3p ; hsa-mir-6868-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-655-5p ; hsa-mir-3667-3p ; hsa-mir-6734-3p ; hsa-mir-329-5p ; hsa-mir-133b ; hsa-mir-133a-3p ; hsa-mir-5587-5p ; hsa-mir-6780a-3p ; hsa-mir-1273f ; hsa-mir-4708-5p ; hsa-mir-6088 ; hsa-mir-4770 ; hsa-mir-143-3p ; hsa-mir-4679 ; hsa-mir-4677-3p ; hsa-mir-4311
Nearest miRNA
hsa-mir-12127/Upstream/380522; hsa-let-7g/Downstream/2857565;
Upstream sequence
AACTTTGCTAACTACTGGGCCCTACAATGTTCTGCAAGGTGTCCCTGGATTTTGCATTGCATTTTCCATTTAGTTAACTTCACAACTGGATGGATGCTTT
Downstream sequence
CTGCCTCTTCTGACCTCTTAAGGAATATGGCTCAATTGCTTTCTGACAAGAGACTTTGGAGGTGTTAGTCCAAGATTTTTAATTCAGCATATTTTTTGAG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Curate