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TVIS44003512
Basic Information
VIS ID
TVIS44003512
Fusion event
HTLV-1-TRIM71 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
32928403/32886911 (Hg38)
End
32928403/32886911 (Hg38)
Orient
-
Location type
Intronic
Target gene
TRIM71
miRNAs that regulate target gene
hsa-let-7c-5p
;
hsa-let-7a-5p
;
hsa-mir-125b-5p
;
hsa-mir-17-5p
;
hsa-let-7b-5p
;
hsa-let-7d-5p
;
hsa-let-7e-5p
;
hsa-let-7f-5p
;
hsa-mir-98-5p
;
hsa-let-7g-5p
;
hsa-let-7i-5p
;
hsa-mir-3607-3p
;
hsa-mir-4458
;
hsa-mir-4500
;
hsa-mir-3927-3p
;
hsa-mir-3935
;
hsa-mir-4495
;
hsa-mir-5093
;
hsa-mir-5680
;
hsa-mir-6831-5p
;
hsa-mir-3117-3p
;
hsa-mir-3169
;
hsa-mir-3908
;
hsa-mir-4503
;
hsa-mir-4759
;
hsa-mir-8083
;
hsa-mir-651-3p
;
hsa-mir-1252-5p
;
hsa-mir-593-5p
;
hsa-mir-383-5p
;
hsa-mir-6839-5p
;
hsa-mir-378j
;
hsa-mir-2115-3p
;
hsa-mir-1243
;
hsa-mir-3156-5p
;
hsa-mir-182-5p
;
hsa-mir-1271-5p
;
hsa-mir-96-5p
;
hsa-mir-183-5p
;
hsa-mir-5572
;
hsa-mir-6855-5p
;
hsa-mir-3170
;
hsa-mir-6819-5p
;
hsa-mir-6812-5p
;
hsa-mir-6737-5p
;
hsa-mir-4325
;
hsa-mir-6858-5p
;
hsa-mir-4689
;
hsa-mir-1224-5p
;
hsa-mir-3915
;
hsa-mir-4473
;
hsa-mir-4671-3p
;
hsa-mir-6881-5p
;
hsa-mir-1256
;
hsa-mir-4653-3p
;
hsa-mir-4784
;
hsa-mir-3150b-3p
;
hsa-mir-3614-5p
;
hsa-mir-454-3p
;
hsa-mir-4295
;
hsa-mir-3666
;
hsa-mir-301b-3p
;
hsa-mir-301a-3p
;
hsa-mir-130b-3p
;
hsa-mir-130a-3p
;
hsa-mir-4761-3p
;
hsa-mir-2110
;
hsa-mir-6780b-5p
;
hsa-mir-4725-3p
;
hsa-mir-4271
;
hsa-mir-4468
;
hsa-mir-7155-5p
;
hsa-mir-637
;
hsa-mir-8089
;
hsa-mir-4700-5p
;
hsa-mir-4667-5p
;
hsa-mir-1298-3p
;
hsa-mir-2278
;
hsa-mir-1276
;
hsa-mir-3686
;
hsa-mir-452-3p
;
hsa-mir-6792-5p
;
hsa-mir-202-3p
;
hsa-mir-203a-3p
;
hsa-mir-34c-3p
;
hsa-mir-6868-3p
;
hsa-mir-6086
;
hsa-mir-377-5p
;
hsa-mir-655-5p
;
hsa-mir-3667-3p
;
hsa-mir-6734-3p
;
hsa-mir-329-5p
;
hsa-mir-133b
;
hsa-mir-133a-3p
;
hsa-mir-5587-5p
;
hsa-mir-6780a-3p
;
hsa-mir-1273f
;
hsa-mir-4708-5p
;
hsa-mir-6088
;
hsa-mir-4770
;
hsa-mir-143-3p
;
hsa-mir-4679
;
hsa-mir-4677-3p
;
hsa-mir-4311
Nearest miRNA
hsa-mir-12127/Upstream/380522; hsa-let-7g/Downstream/2857565;
Nearest TSS
ENST00000440867/Upstream/68893;
ENST00000330953/Downstream/64663;
Nearest CpG islands
None/Target,
chr3-CpG: 148/Upstream/64988
,
chr3-CpG: 67/Downstream/209680
Upstream sequence
AACTTTGCTAACTACTGGGCCCTACAATGTTCTGCAAGGTGTCCCTGGATTTTGCATTGCATTTTCCATTTAGTTAACTTCACAACTGGATGGATGCTTT
Downstream sequence
CTGCCTCTTCTGACCTCTTAAGGAATATGGCTCAATTGCTTTCTGACAAGAGACTTTGGAGGTGTTAGTCCAAGATTTTTAATTCAGCATATTTTTTGAG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Sample Information
×
Sample name
ATL14-R
Sample type
Nontumor
Age
35
Gender
Female
CpG Island Information
×
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