Basic Information
VIS ID
TVIS44003516
Fusion event
HTLV-1-LOC100506885 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
19740378/19740147 (Hg38)
End
19740378/19740147 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC100506885
Nearest miRNA
hsa-mir-3691/Upstream/1168267; hsa-mir-10398/Downstream/7407479;
Nearest TSS
ENST00000381078/Upstream/5580; ENST00000378700/Downstream/9546;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/48073, chr6-CpG: 64/Downstream/64476
Nearby gene
ID4(+97223) ;
Upstream sequence
GAATAAAAGTAAATAGGAAATCATGTTTAATACACCAAATCAATGAAAAGCATATAAAAGTTAAAATTGTCCTTTTTCATGAAGCCCCCAACTGTGTGCT
Downstream sequence
GGTTGAAGAAATGACAGATCTTCTTGAGTTGACTGCTGTGTATATATGTTCCCTGATGCAACCTGAAGTTCTCTGTAGTGAACGTTAGTTCCTGAAATTA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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