Basic Information
VIS ID
TVIS44003520
Fusion event
HTLV-1-chr10 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p15.3
Reference genome
GRCh37/hg19
Start
2136788/2094594 (Hg38)
End
2136788/2094594 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-5699/Upstream/18505; hsa-mir-107/Downstream/1896566;
Nearest TSS
ENST00000439456/Upstream/22749; ENST00000421077/Downstream/71738;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/356770, chr10-CpG: 26/Downstream/220460
Nearby gene
MIR6072(No orient, 18505)
Upstream sequence
CTCTTGCCCTACATTATATTCAATCTGTCTTGCTACTGATTGTTTAAAGAGGCAGAAAGTTACAATTACTTTAGCTAAAAAGGCAATGAAAGAGGCTGAT
Downstream sequence
TCACAGAATAAAAATGATCCTTCCCACGGCCCTGGCCCTGGCTCCATACTTGCAATTCACTTTCATCCTCAGTCCCATCTGCTGCTCCAGGTCCCTCAAC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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