Basic Information
VIS ID
TVIS44003522
Fusion event
HTLV-1-chr11 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q12.2
Reference genome
GRCh37/hg19
Start
59881951/60114478 (Hg38)
End
59881951/60114478 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-129-2/Upstream/519320; hsa-let-7a-2/Downstream/94593;
Nearest TSS
ENST00000527297/Upstream/25814; ENST00000529950/Downstream/46344;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/216094, chr11-CpG: 21/Downstream/400832
Nearby gene
MS4A2(+16011) ;
Upstream sequence
tctgtaagtcagttggggaacttaggattttatttttggtttacagtctggatggtctagttgtgatctccagcagctatagggcctttaccagttcgta
Downstream sequence
gtacaggccttggtggggtggggCATGCTGGGGCTTCTTTATTGAAGGTTATGGAGGAGGTGATGCAGGCACTCTTGGCCAAATTGAAATAGGGAAGTTG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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