Basic Information
VIS ID
TVIS44003534
Fusion event
HTLV-1-BLOC1S5-TXNDC5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p24.3
Reference genome
GRCh37/hg19
Start
7940825/7940592 (Hg38)
End
7940825/7940592 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
BLOC1S5-TXNDC5
Nearest miRNA
hsa-mir-3691/Upstream/1771157; hsa-mir-10398/Downstream/2499125;
Nearest TSS
ENST00000381078/Upstream/29778; ENST00000645232/Downstream/77467;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/29407, chr6-CpG: 41/Downstream/45508
Upstream sequence
aacaaaaagaaaaaagaagaaagagagagagaaagaaaatgagagagaagaaaaaagaaacgaagagaaagaatgaaagaaagaagaaagagaaagaaga
Downstream sequence
aagaaagaaagaaagaaagaaagaaagaaagagagagagagagaaagaaagaaagaaagaaagaaagaatgaACGGAAGGAAGGAAGGAAGGGGCGGCGG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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