Basic Information
VIS ID
TVIS44003550
Fusion event
HTLV-1-MIR548N integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q31.2
Reference genome
GRCh37/hg19
Start
179270989/178406262 (Hg38)
End
179270989/178406262 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
FRA2G
Target gene
MIR548N
Nearest miRNA
hsa-mir-10b/Upstream/1092380; hsa-mir-1244-1/Downstream/1454574;
Nearest TSS
ENST00000437798/Upstream/82692; ENST00000442036/Downstream/7677;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/210845, chr2-CpG: 36/Downstream/7338
Upstream sequence
gatgctactgctcagctacttggtgtgtctgttgtgctgtggtctgtgccttggcatgcaaggtacatgaagcagggtcaatgaaaattgtggaaagtta
Downstream sequence
tagagtacatagaggtttaacagtcttatggaagagtgtataacagtccgttcactcttgctatagtaattctagtatttattgcatggtgaaagtctac
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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