VISDB Viral Integration Site DataBase

VIS ID

TVIS44003574

Fusion event

HTLV-1-PCBD2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr5

Cytoband

q31.1

Reference genome

Start

End

134266734/134931044 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-4503 ; hsa-mir-4291 ; hsa-mir-873-5p ; hsa-mir-761 ; hsa-mir-3619-5p ; hsa-mir-214-3p ; hsa-mir-3617-3p ; hsa-mir-922 ; hsa-mir-6165 ; hsa-mir-34a-3p ; hsa-mir-4282 ; hsa-mir-196a-3p ; hsa-mir-3663-3p ; hsa-mir-4709-5p ; hsa-mir-4280 ; hsa-mir-6514-3p ; hsa-mir-7977 ; hsa-mir-6847-3p ; hsa-mir-6811-3p ; hsa-mir-214-5p ; hsa-mir-383-3p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-3187-3p ; hsa-mir-4435 ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-548s ; hsa-mir-6788-3p ; hsa-mir-378a-5p ; hsa-mir-6131 ; hsa-mir-4755-3p ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-3663-5p ; hsa-mir-3653-5p ; hsa-mir-1306-3p ; hsa-mir-6513-3p ; hsa-mir-1273a ; hsa-mir-1273c ; hsa-mir-25-3p ; hsa-mir-32-5p ; hsa-mir-335-5p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-4325 ; hsa-mir-4486 ; hsa-mir-4649-5p ; hsa-mir-508-5p ; hsa-mir-515-5p ; hsa-mir-519d-5p ; hsa-mir-519e-5p ; hsa-mir-5695 ; hsa-mir-6512-3p ; hsa-mir-661 ; hsa-mir-6720-5p ; hsa-mir-6729-5p ; hsa-mir-766-3p ; hsa-mir-7703 ; hsa-mir-92a-3p ; hsa-mir-92b-3p ; hsa-mir-939-3p

Nearest miRNA

hsa-mir-10397/Upstream/705192; hsa-mir-103a-1/Downstream/871941;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/25420, chr5-CpG: 176/Downstream/96358

Upstream sequence

tcttgctctgttgcccacgctggaatgcagtggcatgatcgtggctcactgcaaccttcacctcccaggttcacgccattctcccacctcagcctaccga

Downstream sequence

gtagctgggactacaggcacccaccaccatgcccggctaatttttttttatttttagtaaagacagggtttcaccgtgttagccaggatggtctcgatct