Basic Information
VIS ID
TVIS44003592
Fusion event
HTLV-1-chr16 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q12.2
Reference genome
GRCh37/hg19
Start
52866401/52832489 (Hg38)
End
52866401/52832489 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1225/Upstream/2090112; hsa-mir-11401/Downstream/3413031;
Nearest TSS
ENST00000527434/Upstream/180384; ENST00000561869/Downstream/220360;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/284791, chr16-CpG: 54/Downstream/222315
Nearby gene
CHD9(+222544) ;
Upstream sequence
CTTGGCAACAACTGTGTTCTTAGCAACTGAAAGGCTGTTTTTCACTTCCATCCATCTATGTTTCCAAATGTGTCCTGGGAGGTTGAAGAGGCTACAAGAC
Downstream sequence
TAACCTTCAAAGAAGGGAGCATTTCCCAGACTTTTAAAAGTTATCAAATTCCATTATATTTGATGCTAGATTCCAATGCCTCAAAAACAATATTTATGTG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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