Basic Information
VIS ID
TVIS44003597
Fusion event
HTLV-1-chr21 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
18382200/17009881 (Hg38)
End
18382200/17009881 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7c/Upstream/419556; hsa-mir-155/Downstream/1676209;
Nearest TSS
ENST00000624081/Upstream/136190; ENST00000613691/Downstream/429009;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/1279397, chr21-CpG: 138/Downstream/502607
Nearby gene
MIR99AHG(No orient, 400106)
Nearest cancer related gene
MIR99AHG(OG, No orient, 400106)
Upstream sequence
tctcttgtctgccaccatgtgaaatgtgcctttcaccttctgccatgattgtgagtcctcttcagccatgtggaactgagagtctattaaacctctttct
Downstream sequence
tttgtaaattgcccagtctcaggtatgtctttattcacagcataaaaatggactaataGAGAGATTAAAAAGAGGTAAGAGAATCAAATTATGATATCAA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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