Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene561274755595179356000181560110515605160456004330560110825603123256035211560277095603092755999490560009185599641955997834560195595602085056039634
Basic Information
VIS ID
TVIS44003605
Fusion event
HTLV-1-PSPH integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
56107327/56039634 (Hg38)
End
56107327/56039634 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA7A
Target gene
PSPH
miRNAs that regulate target gene
hsa-mir-122-5p ; hsa-mir-16-5p ; hsa-mir-296-3p ; hsa-mir-4444 ; hsa-mir-5696 ; hsa-mir-340-5p ; hsa-mir-496 ; hsa-mir-3691-3p ; hsa-mir-4729 ; hsa-mir-3163 ; hsa-mir-1208 ; hsa-mir-1303 ; hsa-mir-1304-3p ; hsa-mir-3658 ; hsa-mir-483-5p ; hsa-mir-6760-3p ; hsa-mir-7856-5p
Nearest miRNA
hsa-mir-1183/Upstream/11157834; hsa-mir-10399/Downstream/916151;
Nearest TSS
ENST00000635602/Upstream/5462; ENST00000493855/Downstream/11654;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/74424, chr7-CpG: 105/Downstream/11718
Upstream sequence
tgggaggccaaggcaggcagatcacgatgtcaggagatcgagaccatcctggccaacatggtgaaagcccatctctactaaaatacaaaaaattagctgg
Downstream sequence
gcatggtagtacgtgcctgtagtcccacctacttgtgaggctgaagcagggaaatcgcttgaacccaggaagtggaggttgcagtaagccgagattgcac
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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