Basic Information
VIS ID
TVIS44003631
Fusion event
HTLV-1-TTC17 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
43487307/43465757 (Hg38)
End
43487307/43465757 (Hg38)
Orient
-
Location type
Intronic
Target gene
TTC17
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-16-5p
Nearest miRNA
hsa-mir-1343/Upstream/7455553; hsa-let-7a-2/Downstream/93899;
Nearest TSS
ENST00000527297/Upstream/14577; ENST00000529140/Downstream/24040;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/106267, chr11-CpG: 20/Downstream/56528
Upstream sequence
cacacgggtaccaagaccattcaatggggaaaagatggtctcttcaaaaagtggtgttagggaaactgtatattcatatgcaaaagaatgaagttggacc
Downstream sequence
cttaccttatatcataggcaaaagttaactcaaaatggtccaaagacctaagtgtaagacctaaaactgtacaactcttggaagaaaacagaggaaaaaa
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Curate