Basic Information
VIS ID
TVIS44003661
Fusion event
HTLV-1-chr14 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
43481694/43012491 (Hg38)
End
43481694/43012491 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-208a/Upstream/6060100; hsa-mir-1185-1/Downstream/4748504;
Nearest TSS
ENST00000550708/Upstream/599918; ENST00000557465/Downstream/1372054;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/1405365, chr14-CpG: 22/Downstream/1874978
Nearby gene
LRFN5(+1107942) ;
Upstream sequence
CCTAAGCCATTAACAGACTGCCTTCAACAATTGTAAGCCTATAATTTATGTAAAATAGATTAATGTGAATCCCCCCTCCTATTATGAGCTTCAGTTGAGC
Downstream sequence
TTTACATAACAAAAATTAAATGAGAGTCATAATTTTAGTCATCATGGAGAAATTTTTTAAACAATATAAAGTTCATCTACCTCTTAGCCCTAAATGTCTA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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