Basic Information
VIS ID
TVIS44003673
Fusion event
HTLV-1-TBCE integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q42.3
Reference genome
GRCh37/hg19
Start
235600985/235437670 (Hg38)
End
235600985/235437670 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1H
Target gene
TBCE
miRNAs that regulate target gene
hsa-mir-423-3p
Nearest miRNA
hsa-mir-101-1/Upstream/247554; hsa-mir-1537/Downstream/415330;
Nearest TSS
ENST00000473358/Upstream/3515; ENST00000646661/Downstream/3152;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/108825, chr1-CpG: 148/Downstream/66119
Upstream sequence
ggaggctggggcaggctgatcgctgcagtccaggagtttgagaccagcctgggcaatcttgtgaaaccccatctctacaaaaaatacaaaaattagctgc
Downstream sequence
atggtggcacgcgcctgtaagtgcttgtagtcccagctactcaggaggctgaagtgggagaatcacctgagcccgggaggccaaggctgcagtgagccat
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Curate