Basic Information
VIS ID
TVIS44003688
Fusion event
HTLV-1-ZNF804B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q21.13
Reference genome
GRCh37/hg19
Start
88696388/89067074 (Hg38)
End
88696388/89067074 (Hg38)
Orient
-
Location type
Intronic
Target gene
ZNF804B
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-10525/Upstream/13151805; hsa-mir-10399/Downstream/3136941;
Nearest TSS
ENST00000635602/Upstream/271353; ENST00000611114/Downstream/151080;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/307105, chr7-CpG: 98/Downstream/1051504
Upstream sequence
ttatcatcctacatatttaatacctaaatatctaactcttttttctacaccaaattgtataagcttcacatctcataaaattgggatccaacactgGTTA
Downstream sequence
CACTtgtatcagtcagggttcagtcagagaagctgaTAAGCTACCGATCAATCTATCTGTCTACCAACCTACCTACCtataaagaaacatgtattataag
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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