Basic Information
VIS ID
TVIS44003740
Fusion event
HTLV-1-chr17 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
38047147/39890894 (Hg38)
End
38047147/39890894 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1180/Upstream/164333; hsa-mir-10226/Downstream/135438;
Nearest TSS
ENST00000595228/Upstream/22678; ENST00000578478/Downstream/15044;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/22510, chr17-CpG: 78/Downstream/36079
Nearby gene
ZPBP2(+12998) ;
Upstream sequence
aggtcaggagttcgagaccagcctggccaacatagtgaaaccctgtctctactaaaaatacaaaaattagctgggtgtggtggtgggtgcctgtaatccc
Downstream sequence
agctacttgggaggctgaggcaggagaatcgcttgaacccaggagacagagatggcagtgagccagattgtgcctctgcactccagggcaacagtgacac
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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