Basic Information
VIS ID
TVIS44003760
Fusion event
HTLV-1-GUSBP4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
58244818/57918540 (Hg38)
End
58244818/57918540 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
GUSBP4
Nearest miRNA
hsa-mir-10398/Upstream/528328; hsa-mir-10524/Downstream/13458420;
Nearest TSS
ENST00000381078/Upstream/4629; ENST00000420759/Downstream/42898;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/64375, chr6-CpG: 39/Downstream/42611
Upstream sequence
TTTACCTCTTCCCTCTCACCTCATCATGTTCATTCATTCATCCCTTTTCCATTCTCACTTTTAAGCTTTAACCTTTCAAAAGCCTATCTTCCCCTATAAG
Downstream sequence
TAATGTATTGTAACTCCCGCCATCACCATATCCTTCTCCAACCAACCAAACTGCCATCCTGAGTTTATGGAAAGTCCATAAACTAAGAAGAAATGGGAAA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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