Basic Information
VIS ID
TVIS44003768
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p31.1
Reference genome
GRCh37/hg19
Start
80625807/80160122 (Hg38)
End
80625807/80160122 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA1L
Nearest miRNA
hsa-mir-101-1/Upstream/3099920; hsa-mir-11399/Downstream/4973672;
Nearest TSS
ENST00000473358/Upstream/45179; ENST00000418041/Downstream/214499;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/1153270, chr1-CpG: 24/Downstream/170850
Upstream sequence
taaagaggcagatatcttgaCGtataacggccaaatgggttcttgcctgctgcccagacagattcaatttattaagacagggaaattgcaatagagaaag
Downstream sequence
agtttaattcactcagagctgcctgtacaggagacccaagttttcttattcctcaaatcagtctccctggaaattcagagactgggatttttaaggataa
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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