Basic Information
VIS ID
TVIS44003771
Fusion event
HTLV-1-CHKA integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
67864893/68097426 (Hg38)
End
67864893/68097426 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA11H
Target gene
CHKA
Nearest miRNA
hsa-mir-10392/Upstream/52469; hsa-let-7a-2/Downstream/985750;
Nearest TSS
ENST00000527297/Upstream/7546; ENST00000530842/Downstream/23402;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/58282, chr11-CpG: 123/Downstream/23621
Upstream sequence
GAAGCGTTTTTGAAATTGCCCGTGTGggccgggcacggtggctcacgcctgtaatcccagcactttgggaggccgaggcgggtggatcacaaggtcaagg
Downstream sequence
aatctagaccatcctggctaacacggtgaaaccccgtctctactaaaaaaatacaaaaaattagccaggcgtggtggcaggtgcctgtagtcccagcaac
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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