Basic Information
VIS ID
TVIS44003774
Fusion event
HTLV-1-chr12 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q21.33
Reference genome
GRCh37/hg19
Start
89675905/89282128 (Hg38)
End
89675905/89282128 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA12B
Nearest miRNA
hsa-let-7i/Upstream/2536979; hsa-mir-1178/Downstream/5279661;
Nearest TSS
ENST00000382841/Upstream/262449; ENST00000611513/Downstream/27425;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/701239, chr12-CpG: 248/Downstream/69263
Nearby gene
DUSP6(-65697) ;
Nearest cancer related gene
DUSP6(TSG, -65697) ;
Upstream sequence
tcaagtaacccaccctcttgagccttccaaagtgctgggattacaggtgtgagccactgcacccaaccCTAAATTATTTCTTAATTGATATTGGTTTACT
Downstream sequence
GCCTTTTACCATGAGCTGATATGCATAATCTTATCTGGCTCTCATAAGAAATTGTCTGGGAAAATATGATTCCTCGCTATTTTTTTTTCCCATGGggagt
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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