Basic Information
VIS ID
TVIS44003778
Fusion event
HTLV-1-chr13 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
55132748/54558613 (Hg38)
End
55132748/54558613 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1297/Upstream/246565; hsa-mir-1267/Downstream/615841;
Nearest TSS
ENST00000623511/Upstream/425747; ENST00000616396/Downstream/382230;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/1356403, chr13-CpG: 25/Downstream/2582224
Nearby gene
MIR1297(-246565) ;
Nearest cancer related gene
MIR1297(TSG, -246565) ;
Upstream sequence
gattacagcctgagagtgtatagtagaaaccagctaagcaatagccagactccactgtcacagagactgcagtaagaaatgcatgttgctgtaagttgct
Downstream sequence
aaatttgtggtaagttgctatacaacaatTAATAAAAAATCTCTAAAATAACTACCAGAAAAACTCAATTACAATCAGAAACATTGTCCCTACCTCCCAT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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