Basic Information
VIS ID
TVIS44003786
Fusion event
HTLV-1-SLC47A1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
19438686/19535373 (Hg38)
End
19438686/19535373 (Hg38)
Orient
+
Location type
Intronic
Target gene
SLC47A1
miRNAs that regulate target gene
hsa-mir-6770-3p ; hsa-mir-4730 ; hsa-mir-939-5p ; hsa-mir-1343-5p ; hsa-mir-3144-5p ; hsa-mir-920 ; hsa-mir-6726-5p ; hsa-mir-5591-5p ; hsa-mir-4300 ; hsa-mir-6787-5p ; hsa-mir-663a ; hsa-mir-1908-5p ; hsa-mir-4467 ; hsa-mir-4749-5p ; hsa-mir-4706 ; hsa-mir-8072 ; hsa-mir-3960 ; hsa-mir-1307-3p ; hsa-mir-6889-5p ; hsa-mir-6777-5p ; hsa-mir-3189-3p ; hsa-mir-212-5p ; hsa-mir-6784-5p ; hsa-mir-4655-5p ; hsa-mir-4665-5p ; hsa-mir-5010-5p ; hsa-mir-1275 ; hsa-mir-4525 ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-625-5p ; hsa-mir-6883-5p ; hsa-mir-6825-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-3616-3p ; hsa-mir-4680-5p ; hsa-mir-7155-5p ; hsa-mir-637 ; hsa-mir-4700-5p ; hsa-mir-8089 ; hsa-mir-4667-5p ; hsa-mir-330-5p ; hsa-mir-326 ; hsa-mir-181d-3p ; hsa-mir-514a-5p ; hsa-mir-5008-5p ; hsa-mir-6851-3p ; hsa-mir-7160-3p
Nearest miRNA
hsa-mir-1180/Upstream/190799; hsa-mir-10226/Downstream/7758537;
Nearest TSS
ENST00000595228/Upstream/1493; ENST00000575362/Downstream/20136;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/994, chr17-CpG: 58/Downstream/44540
Upstream sequence
aaaatacaaaaattagccagacgtggtggcgggcgcctgtagtgccagctactccagaggctgaggcacgagaatcgcttgaacctgggaagtggaggtt
Downstream sequence
acagtgagccaggatggtgccactgcactccagcctgaacaacagagtaagacttggtctcaaaaaacaaaacaaaacaaaacaaaaACACCTCATggct
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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