Basic Information
VIS ID
TVIS44003800
Fusion event
HTLV-1-FER1L4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q11.22
Reference genome
GRCh37/hg19
Start
34167785/35579863 (Hg38)
End
34167785/35579863 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
FER1L4
Nearest miRNA
hsa-mir-103a-2/Upstream/125766; hsa-mir-1-1/Downstream/2936700;
Nearest TSS
ENST00000382410/Upstream/23253; ENST00000462896/Downstream/36029;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/37574, chr20-CpG: 140/Downstream/20934
Nearest cancer related gene
FER1L4(TSG, No orient, 0)
Upstream sequence
aaaatacaaaaattagctgggcgtggtggtgagcacctgtaatctcagctactcgggagactgaggcaggagaatcgcttgaaaacagaaggtggaggtt
Downstream sequence
gcagtgagccaaggtcacaccactgtactgcagtctgggcaacaacagcaaaactccatctcaaaaaaaaaaaaaaaaaaaaagggacacaatcctggat
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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