Basic Information
VIS ID
TVIS44003819
Fusion event
HTLV-1-LOC105373347 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q27.3
Reference genome
GRCh37/hg19
Start
146300388/147218870 (Hg38)
End
146300388/147218870 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRAXE ; FRAXF
Target gene
LOC105373347
Nearest miRNA
hsa-let-7f-2/Upstream/5279; hsa-mir-105-1/Downstream/6956;
Nearest TSS
ENST00000429181/Upstream/37806; ENST00000621447/Downstream/682589;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/598107, chrX-CpG: 91/Downstream/692703
Nearby gene
MIR513A1(-5279) ;
Upstream sequence
GATCCACATCTTAATTTTATCAAACACTGTATCCACATTATGATGTTAATGGTATTATGCTATTATTTCATTACTGCTTTTCATGCTTTTCATACCTTGT
Downstream sequence
ATGTGTTTTCCAAGTTGTTCTTCAATAAATAGGAATTACCCTCATGGTCAGAAAGATATCAATAAAAATATAATTTGCTCTGACAGAATTCTGATATAAG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Curate