Basic Information
VIS ID
TVIS44003831
Fusion event
HTLV-1-CLDN10-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q32.1
Reference genome
GRCh37/hg19
Start
96147035/95494781 (Hg38)
End
96147035/95494781 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA13D
Target gene
CLDN10-AS1
Nearest miRNA
hsa-mir-1297/Upstream/3004561; hsa-mir-1267/Downstream/932448;
Nearest TSS
ENST00000623511/Upstream/61177; ENST00000376855/Downstream/39129;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/60759, chr13-CpG: 59/Downstream/57656
Upstream sequence
AAGTGTACTTATCTCTGAATAAAACAGTTGCTTTCCCAAACTTCCTCTAGCGTGTTCTGAAGAAcagagaatcttaggatggtagatacggacagggcct
Downstream sequence
ttaagaccacctagtctggccccatcatctgacagatgaacagacatgaaaccTCATCGTAAGATCACACAACACCTTGATGGCTTTTGTGTAATTTGTT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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