Basic Information
VIS ID
TVIS44003839
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q33.3
Reference genome
GRCh37/hg19
Start
205112824/204248101 (Hg38)
End
205112824/204248101 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA2I
Nearest miRNA
hsa-mir-10b/Upstream/15114990; hsa-mir-1244-1/Downstream/2535133;
Nearest TSS
ENST00000437798/Upstream/13116; ENST00000456384/Downstream/225736;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/712655, chr2-CpG: 83/Downstream/297115
Nearby gene
ICOS(+286526) ;
Upstream sequence
caagaagaaattcaaagaaaaaagaaaaaaaatcaaagaaaaaaaAAGGAAAAAGAAAAAAGAATTGAGAAGAATAGGGTCTTAAGTTGACCTTAAGAGA
Downstream sequence
GAATGTGGCTTGAATCATCTCCATCCAGTGACTTATAAGAAAGTGGACAAGATTTTCAAAGAAATAAGGATAAAGATAGAAAGGGGGAAGAGACAAAAGC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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