Basic Information
VIS ID
TVIS44003842
Fusion event
HTLV-1-FH integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q43
Reference genome
GRCh37/hg19
Start
241670062/241506762 (Hg38)
End
241670062/241506762 (Hg38)
Orient
-
Location type
Intronic
Target gene
FH
miRNAs that regulate target gene
hsa-mir-34a-5p ; hsa-mir-26b-5p ; hsa-mir-320a
Nearest miRNA
hsa-mir-101-1/Upstream/374416; hsa-mir-3124/Downstream/1839414;
Nearest TSS
ENST00000473358/Upstream/82364; ENST00000484229/Downstream/6914;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/82179, chr1-CpG: 76/Downstream/12411
Nearest cancer related gene
FH(TSG, No orient, 0)
Upstream sequence
ACAGAGACTTGGGAAGCTAATGACTCACTGAATAGCACAGGAAGGTAACAGTTTGCATTGAAGGACCTTCCAAAAAGAATAGGAGGTAACGGTAGAGTCA
Downstream sequence
GATCATAGCATCAATGTGCCAATGTCAACACTGGTTCCAAATTTTGACATGCCTTAATTAAAGCAACCACAGAATTTATGTTTTGAACACagaaagggct
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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