Basic Information
VIS ID
TVIS44003894
Fusion event
HTLV-1-PRTFDC1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
25193680/24904751 (Hg38)
End
25193680/24904751 (Hg38)
Orient
+
Location type
Intronic
Target gene
PRTFDC1
Nearest miRNA
hsa-mir-1265/Upstream/628970; hsa-mir-107/Downstream/3384507;
Nearest TSS
ENST00000439456/Upstream/181083; ENST00000610158/Downstream/47833;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/179864, chr10-CpG: 72/Downstream/47430
Upstream sequence
GAATACATCTGAACTTCTAGGGATCTCTAAGAATCCTGGAAAAGAGACTAAGCCATGGTTTAGAGAGACCACTCTTATTTGTTCCTTTACCTATGCTACT
Downstream sequence
GATCCTGTCCATGTGCCCCTCTTCACCAGCCTGACACCTTCTGTGGATTTCATCCCAAATTCTATCCTCCACCTTCAACCCCATTTCATattccctagtc
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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