Basic Information
VIS ID
TVIS44003902
Fusion event
HTLV-1-chr15 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q12
Reference genome
GRCh37/hg19
Start
26656487/26411340 (Hg38)
End
26656487/26411340 (Hg38)
Orient
+
Location type
Intronic
Target gene
LINC02248 ; LOC105370740
Nearest miRNA
hsa-mir-1268a/Upstream/562515; hsa-mir-10393/Downstream/2015151;
Nearest TSS
ENST00000557528/Upstream/16268; ENST00000450324/Downstream/22034;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/328591, chr15-CpG: 37/Downstream/217610
Nearby gene
GABRB3(-132207) ;
Upstream sequence
ACCATGGGTAATATAAAATGAGTGGCGGTAGGTGACCCTCGAATAAATGAAAGTGCCGTTTTCCCATTTATCCatccattcattctacaaatatttactg
Downstream sequence
agcatgtaccatgagcccagcagacatagcccctgtccgcaatatgctcaaagattactgagggcataaataagaaaatcaccaggccaggcacggtggc
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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