VISDB Viral Integration Site DataBase

VIS ID

TVIS44003904

Fusion event

HTLV-1-CACNA1A integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr19

Cytoband

p13.13

Reference genome

Start

End

13419200/13308386 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-3p ; hsa-mir-4307 ; hsa-mir-33a-3p ; hsa-mir-548c-3p ; hsa-mir-744-5p ; hsa-mir-4749-5p ; hsa-mir-4706 ; hsa-mir-4734 ; hsa-mir-6893-3p ; hsa-mir-370-3p ; hsa-mir-4485-5p ; hsa-mir-2355-5p ; hsa-mir-6516-3p ; hsa-mir-642b-5p ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-5695 ; hsa-mir-519d-5p ; hsa-mir-6793-3p ; hsa-mir-186-3p ; hsa-mir-148a-5p ; hsa-mir-1224-3p ; hsa-mir-1231 ; hsa-mir-1260a ; hsa-mir-1260b ; hsa-mir-1273g-5p ; hsa-mir-147a ; hsa-mir-188-5p ; hsa-mir-203a-5p ; hsa-mir-212-5p ; hsa-mir-346 ; hsa-mir-3671 ; hsa-mir-3911 ; hsa-mir-4288 ; hsa-mir-4687-3p ; hsa-mir-4762-5p ; hsa-mir-4780 ; hsa-mir-5087 ; hsa-mir-532-3p ; hsa-mir-605-5p ; hsa-mir-607 ; hsa-mir-623 ; hsa-mir-632 ; hsa-mir-644a ; hsa-mir-647 ; hsa-mir-6747-3p ; hsa-mir-6752-3p ; hsa-mir-6778-3p ; hsa-mir-6780b-3p ; hsa-mir-6791-3p ; hsa-mir-6828-3p ; hsa-mir-6829-3p ; hsa-mir-6836-3p ; hsa-mir-6842-3p ; hsa-mir-6866-3p ; hsa-mir-7106-3p ; hsa-mir-7113-3p ; hsa-mir-767-3p ; hsa-mir-7974

Nearest miRNA

hsa-mir-10395/Upstream/367846; hsa-let-7e/Downstream/527901;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/9069, chr19-CpG: 56/Downstream/197552

Upstream sequence

CGGGGGAGGCAGGGCCCCGGAGTCAGCCCTCGAAACACGAGGCTCACTTTCCCAACTTTCTGGAGGCGGCCCCACCATGTCCCCCATCCCCACCCCCTGT

Downstream sequence

ACAAATGTCCAGGAACCCCAAAGACTTACTTTGTGACTTTGAAAATACGCAATAACCTGAGGGCTCGTAACACGCTGATTCCAAAGGATGTGCCAGGTTT