Basic Information
VIS ID
TVIS44003916
Fusion event
HTLV-1-chr5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q35.2
Reference genome
GRCh37/hg19
Start
174158704/174731701 (Hg38)
End
174158704/174731701 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA5G
Nearest miRNA
hsa-mir-10397/Upstream/1384165; hsa-mir-1229/Downstream/20033;
Nearest TSS
ENST00000502646/Upstream/7099; ENST00000510150/Downstream/19603;
Nearest CpG islands
chr5-CpG: 88/Target, None/Upstream, None/Downstream
Nearby gene
MSX2(+802) ;
Upstream sequence
TCTGTTGCCCAAATAAATCTGAAGTGGTTCCTGATGATTGATACCTTTCCGAGGTCAGTGTTCAGATGGGAGGCTCCGGTGACTCGGAACAGAGGCAGAA
Downstream sequence
AGGATGCGAGGACTTCTTGCTGCGTAAACAGCGCGGCGGGCAGATTGGCACCTGGCACCTACCAGGACTGGCGCTTCGTCCCGCGTTTCCATTGTGCCCG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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