Basic Information
VIS ID
TVIS44003935
Fusion event
HTLV-1-FABP12 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q21.13
Reference genome
GRCh37/hg19
Start
82501208/81588973 (Hg38)
End
82501208/81588973 (Hg38)
Orient
-
Location type
Intronic
Target gene
FABP12
Nearest miRNA
hsa-mir-12123/Upstream/1347500; hsa-mir-10400/Downstream/9616512;
Nearest TSS
ENST00000518652/Upstream/57595; ENST00000297265/Downstream/85448;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/66543, chr8-CpG: 48/Downstream/41590
Nearby gene
FABP12(-57658) ;
Upstream sequence
TATCCCAGGTGGGGGCTGGCAGTGGATATGTCCAAACTTAGAAGTGAATCACGGGAGCTTTAAAGGCTTGAACCCACTTCAATAGGGCATGTTGGAGCCA
Downstream sequence
CAGCCCATCCCTAAGCACAGCACTCCAGATCAGCAACTATGGATGAGGTGACTGTGACCTCCCTCAGGTTGCATAAGTAGGGATATATTTATGCCTTTCA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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